Genome Sciences Core
Director: Willard Freeman, PhD
Phone: (717) 531-5823
Email: wfreeman@psu.edu
Staff: Robert Brucklacher, BA, BS; Georgina Bixler, BS.
The Genome Sciences Core provides services and analyses for genotyping and gene expression studies ranging from genome-wide studies to focused analyses of specific SNPs, mRNA, or miRNAs. The Core also provides pre-experiment consultation to ensure the best possible results and post-experiment bioinformatic capabilities.
Services Offered:
- RNA Quality Assessment
- mRNA Microarrays (Human, Mouse, Rat)
- SNP Microarrays (up to 1,000,000 SNPs)
- Quantitative Real-Time PCR mRNA and miRNA analyses
- TaqMan SNP Analyses
- Epigenetic Analyses (Chromatin and DNA methylation)
- Bioinformatic Analyses
Major Equipment & Software:
- Agilent 2100 Bioanalyzer
- Agilent Genespring GX 11 Software
- ABI 7900HT qPCR Instrument
- Axon 4000B microarray scanner
- GE Healthcare Codelink Bioarray Parallel Processing System
- Illumina BeadStation system
- Illumina BeadExpress system
- Illumina GenomeStudio Software
- Ingenuity Pathway Analysis Software
- Molecular Devices M2 UV/Vis/Fluor Spectrophotometer
- Nanodrop Spectrophotometer
- Nimblegen Microarray Dryer
- Roche/Nimblegen Hybridization System
- SignalMap Software