Active Protocols

This is a list of protocols that have been approved for GCRC resources. The investigator may or may not be actively recruiting on any specific protocol. Investigators may have other research protocols that are not being performed through the GCRC.

For information regarding the protocols, please contact the recruiter

Abou-Elella, Ashraf

Autoimmune disease and neutropenia 19223

19223

Bixler, Edward

Sleep Disordered breathing in children

98-228

Connor, James

Memory and Aging Study 19955

19955

Craig, Timothy

Efficacy of Venom Immunotherapy in Patients with previous large local reactions to insect stings

18676

Craig, Timothy

In-Vitro Approach to Problems of Clinical Allergy: Insect Sting Anaphylaxis: Determinants of Clinical Reactivity

99-158

Cui, Jian

Neurovascular Control in Diastolic Heart Failure

18448

Cui, Jian

Muscle sympathetic nerve activity responses to stimulation of mechanoreceptors in muscle

21178

Cui, Jian

Roles of 20-hydroxyeicosatetraenoic acids (20-HETE) in exercise pressor reflex

21400

Cui, Jian

Neural Control of Skin Blood Flow During Heat Stress in Congestive Heart Failure Patients

21439
Dodson, William

The Effect of Oral Contraceptive Pills and Endogenous Sex Steroids on Uterine Leiomyoma

2003-192
Eslinger, Paul

Spatially distributed attention in adolescents with Attention Deficit Hyperactivity Disorder

2003-030

Ettinger, Steven

Effects of Gender and Ovarian Cycle Phase on the Skeletal Muscle Interstitium

98-207

Floros, Joanna

Surfactant Proteins and Respiratory Distress Syndrome

95-024

Han, David

The Relationship Between C-Reactive Protein and the Presence and Progression of Hemodynamically Significant Asymptomatic Extracranial Carotid Artery
Atherosclerotic Occlusive Disease

19421EP

Imadojemu, Virginia

Myogenic reflexes in circulatory control

99-118

Imadojemu, Virginia

Determination of vascular resistance in the arm during application of lower body negative pressure and localized forearm negative pressure

2001-337

Koltun, Walter

A Proposal for the Creation of an Inflammatory Bowel Disease Registry

98-057

Lee, Peter

Outcome studies among adults born with incomplete genital development

2001-134

Lee, Peter

Pubertal Gonadotropin Responses to GnRH Analogue (Leuprolide) for Diagnostic Testing

2001-211EP

Legro, Richard

Genetics of Familial Polycystic Ovary Syndrome

97-041

Legro, Richard

Racial Differences in Circulating Sex Steroids:Mechanisms and Effect on Bone

2003-171

Legro, Richard

The Effect of Combination Therapy with
Lifestyle Intervention and Metformin in Females with Polycystic Ovary Syndrome

2003-172

Legro, Richard Phenotype and Genotype in Polycystic Ovary Syndrome
94-088
Legro, Richard

The effect of meals of varying fat and fiber contention postprandial plasma testosterone concentrations

19542
Legro, Richard

Continuous glucose monitoring in pregnant women with polycystic ovary syndrome

19703

Leuenberger, Urs

Influences of age and sex on acute sympathetic vasoconstrictor responsiveness during small muscle dynamic exercise

2004-014

Leuenberger, Urs

Alteration of sympathetic activity and blood pressure and by CPAP therapy in sleep apnea patients

91-033

Leuenberger, Urs

Effects of hypoxia on skeletal muscle vs. venous effluent adenine nucleotides and nitric oxide

18883

Leuenberger, Urs

Effects of systemic hypoxia on MSNA and its relationship to interstitial adenine nucleotides and NE and to skeletal muscle blood flow

18954
Leuenberger, Urs

Effects of inhibitors of metabolic vasodilation during Hypoxia

18813
Leuenberger, Urs

Effects of Repetitive Hypoxic Apnea on Blood Pressure and Sympathetic Reflex Function

2002-231
Leuenberger, Urs

Effects of hypoxia on interstitial metabolites and skeletal muscle blood flow in Obstructive Sleep Apnea (OSA)

2002-232
Leuenberger, Urs

Effects of Sympathetic Neural Blockade on Reactive Hyperemia and Hypoxia Responses in Obstructive Sleep Apnea

2002-253

Lott, Mary

Effect of Diabetes on the Myogenic Response

19460

Lott, Mary

Effects of Endurance Training on the Myogenic

20549

Loughran, Thomas

A Phase II Study of Initial Treatment with Methotrexate in Large Granular Lymphocytic (LGL) Leukemia (E5998)

2003-182
Loughran, Thomas

Pathogenesis of LGL Leukemia

2003-260EP
Loughran, Thomas

Large Granular Lymphocyte (LGL) Leukemia Registry

2003-276

MacNeill, Colin

Collection-mediated innate immunity in volvodynia

2000-114

McCabe, Paul

Progesterone Therapy versus Placebo for Women with Epilepsy

21320

Monahan, Kevin

Limb Neurovascular Control and Aging: MSNA and Blood Flow

21622

Monahan, Kevin

Role of Aldosterone on Autonomic Control in Humans

20350

Monahan, Kevin

Effect of Isometric Handgrip Training on Arterial Blood Pressure

21105

Monahan, Kevin

Influence of Repetitive Hypoxic Apnea on Autonomic and Cardiovascular Control in Humans

19943

Ouyang, Anne

Effect of menstrual cycle and Irritable Bowel Syndrome on the Central Nervous System: processing of gut stimuli

99-073

Ouyang, Anne

Mechano-Physiological Approach to Normal Anorectal Function and the Classification of Defecatory Disorders

2003-368
Pu, Min

Identification of Impending Left Ventricular Dysfunction in Asymptomatic Patients with Severe Mitral Regurgitation: Exercise Echocardiographic and Neurohormonal Studies

2001-368EP
Pu, Min

Identification of Impending Left Ventricular Dysfunction in Asymptomatic Patients with Severe Mitral Regurgitation: Exercise Echocardiographic and Neurohormonal Studies

2003-067
Raja-Khan, Nazia

A pilot study comparing reactive hyperemia in women with Polycystic Ovary Syndrome and controls

19391
Ray, Chester

Effect of bed rest on the vestibulo sympathetic reflex in humans

99-294
Ray, Chester

Influence of Head-Down Rotation on Blood Hormone Levels

2002-092
Ray, Chester

Responses of the Vestibulo-sympathetic Reflex in Endurance Trained Subjects

18794
Ray, Chester

Interactive Effects of Cardiovascular and Vestibular Reflexes

98-217
Ray, Chester

Effects of exercise induced muscle soreness on muscle sympathetic nerve activity: the role of prostaglandins

98-247
Ray, Chester

Influence of Endurance Training on Age-Related Impairment of Vestibular-Mediated Cardiorespiratory Reflexes

21244
Simmons, Zachary

Mutation Analysis, Iron Studies, Magnetic Resonance Imaging, and Cerebrospinal Fluid  Analysis in Amyotrophic Lateral Sclerosis (ALS)

20473
Simmons, Zachary

A Multicenter, Dose Ranging Safety Pharmacokinetics Study of Arimoclomol in Amyotrophic Lateral sclerosis (ALS)

21255
Simmons, Zachary

Early Treatment of ALS With Nutrition and NIPPV

19387
Singareddy, Ravi

Respiratory abnormalities in nocturnal panic attacks

21319

Sinoway, Lawrence

Sympathetic tone and its effects on forearm blood flow

18540

Sinoway, Lawrence

Neurovascular Control in Diastolic Heart Failure

18663

Sinoway, Lawrence

Adrenergic stimulation during low-level handgrip exercise

18759

Sinoway, Lawrence

The effect of static exercise on renal blood flow

2002-116

Sinoway, Lawrence

The effect of exercise on coronary hemodynamics

19426
Sinoway, Lawrence

ATP and interstitial Norepinephrine in Stretched Muscle

21442
Sinoway, Lawrence

Renal hemodynamic responses to physiological stress

19639

Smith, Jill

Effects of Naltrexone on Active Crohn's Disease

21455

Smith, Jill

The Efficacy of Low Dose Naltrexone Therapy in Children with Crohn's Disease

27793

Smith, Jill

OGF & Gemcitabine: Novel Treatment for Pancreatic Cancer Phase I, A Safety and Toxicity Study

20978

Sumner, Andrew

Effects of Hypertriglyceridemia on Blood Viscosity, Inflammatory Markers, and Vascular Function

19991

Thiboutot, Diane

Assessment of sebum production in subjects treated with fibrates or thiazolidinediones

2001-370

Thiboutot, Diane

Analysis of gene expression in the skin of patients treated with isotretinon

2001-371
Thomas, Neal

Individual variability in innate lung host defense: Surfactant protein-A genetic variants and macrophages as contributing partners

19624
Trussell, J C

The Incidence and Treatment of Insulin Resistance Among Men with Erectile Dysfunction

18805

Vgontzas, Alexandros

IL-6 Secretion and Quantity and Quality of Sleep: Age and Gender Effects

99-126

Vgontzas, Alexandros

Effects of Partial Sleep Deprivation on Sleepiness and Cytokine Secretion

2000-125

Vgontzas, Alexandros

Administration of Rosiglitazone in Patients with Sleep Apnea

19403
XU

Irritable Bowel Syndrome and Acupuncture

2000-343
Yang, Qing

Functional MRI Investigation of Olfactory Deficits in Alzheimer's Disease

2000-289EP