Investigator resources

IRB review and approval is required for all research involving human subjects conducted at Penn State Milton S. Hershey Medical Center or Penn State College of Medicine. Approval must be obtained prior to including human subjects in an investigation.  Below are resources for making submissions to the IRB.  New researchers are encouraged to contact the HSPO for consultation with an IRB analyst.

IRB and research protection policies

IRB submission process

Online submissions are made using the Centralized Application Tracking System (CATS IRB) at The system includes templates needed for submission, an Investigator Manual for conducting research at Penn State, and Help Center resources. For hands-on CATS IRB training, see Educational Resources for workshop dates.

Note: To make submissions for Emergency Use of Investigational Test Articles, Review Preparatory to Research, or Research with Decedent Information, see the link below for Forms and Instructions Not in CATS IRB.

Other information