Clinical Trials
The following are trials currently active:
For more information please contact Dr. Rogerio I. Neves M.D., Ph.D. (Contact details)
| Principal Investigator Name | Protocol No. | Title |
| Drabick, Joseph | PSHCI-09-030 | A Phase II Trial of Dasatinib in KIT-Positive Patients with Unresectable Locally Advanced or Stage IV Mucosal, Acral and Vulvovaginal Melanomas (E2607) |
| Drabick, Joseph | PSHCI-10-039 | Phase 1b Open Label, Single Arm, Multicenter Trial to Evaluate the Safety, Tolerance, Response Rate and Immunological Effects of Repeated Intra-tumoral Injections of Adenoviral Transduced Autologous Dendritic Cells Engineered to Express hIL-12(INXN-3001) in Response to an Oral Activator Ligand in Patients with Unresectable Stage III C or IV Malignant Melanoma |
| Drabick, Joseph | PSHCI-11-072 | A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-risk Melanoma |
| Neves, Rogerio | PSHCI-08-059 | Multicenter Selective Lymphadenectomy Trial II (MSLT-II): A Phase III Multi center Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection Versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patients with Molecular or Histopathological Evidence of Metastases in the Sentinel Node, coordinated by the John Wayne Cancer Institute |
| Neves, Rogerio | PSHCI-08-080 | Histological Features of Sentinel Lymph Node Biopsy for Malignant Melanoma as a Predictive Indicator for Completion Lymphadenectomy |
| Drabick, Joseph | PSHCI-09-067 | Phase II Trial of High Dose Interleukin-2 followed by intermittent low dose Temozolomide in patients with Metastatic Malignant Melanoma |
| Neves, Rogerio | PSHCI-11-022 | A phase II, randomized double-blind study of efficacy and safety of two dose levels of LDE225 in patients with locally advanced or metastatic basal cell carcinoma (Novartis) |
| Drabick, Joseph | PSHCI-10-061 | General Protocol for the Acquisition of Whole Blood for the Detection and Characterization of Circulating Tumor Cells and/or Tumor Specific Immunity/Immune Cell Activation for any Malignancy at any Stage of Disease |
| Neves, Rogerio | PSHCI-09-052 | The Collection of Blood, Tissue and Phenotypic Data in Patients diagnosed with Skin Cancers and Subsequent Metastases for Inclusion in a repository and use in outcome studies |
| Neves, Rogerio | PSHCI-10-099 | Phase III Randomized Trial of Surgical Resection With or Without BCG Versus best medical therapy as initial treatment in stage IV melanoma |
| Neves, Rogerio | PSHCI-11-003 | Whole Brain Radiotherapy following local treatment of intracranial metastases of melanoma – A randomized Phase III trial |