Grants

Kevin M. Cockroft, M.D.
Principal Investigator:  Joseph P. Broderick, M.D, University of Cincinnati Neuroscience Institute
Primary Institute:  University of Cincinnati
Role:  Site Principal Investigator
Co-Investigators:  Raymond K. Reichwein, M.D., David C. Good, M.D., Paul Kalapos, M.D., Kerstin Bettermann, M.D., Department of Neurology
Title:  "Interventional Management of Stroke Trial III (IMS III)"
Funding Agency:  National Institutes of Health (5 U01 NS052220-07)
Period:  09/30/2011-07/31/2015
Amount:  $101,836

Principal Investigator:  Daniel F. Hanley, M.D., Department of Neurology
Primary Site:  The Johns Hopkins University
Role:  Site Principal Investigator
Title:  "CLEAR III: Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage"
Funding Agency:  National Institutes of Health (5 U01 NS-062851-04)
Period:  07/01/2009-06/30/2015
Amount:  $17,002


James R. Connor, Ph.D.
Multi PI:  Ian A. Simpson, Ph.D., Department of Neural and Behavioral Sciences
Title:  "Mechanisms and Regulation of Brain Iron Uptake"
Funding Agency:  National Institute of Neurological Disorders and Stroke (5 R01 NS077678-04)
Period:  07/01/2012-06/30/2015
Amount:  $486,641

Co-Investigator:  A.B. Madhankumar, Ph.D.
Title:  "Targeted Delivery of a Potent Anti-Proliferative Metal Chelator to Brain Tumors"
Funding Agency:  PA Tobacco Settlement Funds (TSF)
Period:  07/01/2013-06/30/2015
Amount: $25,000

Multi-PI:  Jeremy N. Rich, M.D., Department of Neurology
Primary Site:  The Cleveland Clinic
Co-Investigator:  A.B. Madhankumar, Ph.D.
Title:  "Glioblastoma Therapy Through Ferritin Targeting"
Funding Agency:  National Cancer Institute (1R01-CA169117-01A1)
Period:  07/01/2013-04/30/2015
Amount:  $238,870

Principal Investigator:  Xuemei Huang, Department of Neurology
Role:  Co-Investigator
Title:  "Multimodal MRI Markers of Nigrostriatal Pathology in Parkinson's Disease"
Funding Agency:  National Institutes of Diabetes and Digestive and Kidney Diseases (1 U01NS082151-01)
Period:  09/01/2014-08/31/2015
Amount:  $887,690


Mark S. Dias, M.D.
Title:  "Pennsylvania Shaken Baby Syndrome (SBS) Prevention and Awareness Program"
Funding Agency:  Commonwealth of Pennsylvania:  Department of Health
Period:  07/01/2012-06/30/2016
Amount:  $73,940
Supplemental Funds:  $219,335
Supplemental Funds:  $586,550

Principal Investigator:  Melanie A. Comito M.D., Department of Pediatrics
Role:  Co-Investigator
Co-Investigators:  Jennifer W. Baccon, M.D., Ph.D., Department of Pathology; Robert J. Greiner, M.D., Department of Pediatrics; Mark R. Iantosca, M.D., Department of Neurosurgery; John F. Kuttesch, M.D, Department of Pediatrics; Heath Mackley, M.D., Department of Radiology; Arabinda K. Choudhary, M.B.B.S., Department of Radiology; Charles Specht, M.D., Department of Pathology
Title:  "Phase II Trial of Molecularly Determined Treatment of Children and Young Adults with Newly Diagnosed Diffuse Intrinsic Pontine Gliomas"
Funding Agency:  Dana Farber Cancer Institute
Period:  10/15/2012-09/30/2015
Amount:  $20,000


Bruce J. Gluckman, Ph.D.
Department of Engineering Science and Mechanics, Department of Neurosurgery
Title:  "CRCNS: Model Based Data Assimilation and Control of Sleep-Wake Regulation in Epilepsy"
Funding Agency:  National Institute of Biomedical Imaging and Bioengineering
Period:  09/17/2014-05/31/2015
Amount:  $295,550

Title:  "7th International Workshop on Seizure Prediction (IWSP7)"
Funding Agency:  National Institute of Neurological Disorders and Stroke (1 R13 NS090888-01)
Period:  09/30/2014-09/29/2015
Amount:  $15,000


Mark R. Iantosca, M.D.
Co-Investigator:  Mark S. Dias, M.D.
Title:  "The Park-Reeves Syringomyelia Registration and Data Use Agreement"
Funding Agency:  Washington University in St. Louis
Period:  08/08/2011-12/31/2015
Amount:  $50,000


Sang Y. Lee, Ph.D.
Title:  "Testing Sponsor Compounds on GBM Cell Lines and Intracranial Brain Tumor Mouse Model"
Funding Agency:  Opal Oncology Limited
Period:  07/01/2014-06/30/2016
Amount:  $32,415

Co-Investigator:  Cara-Lynne Schengrund, Ph.D., Department of Biochemistry and Molecular Biology
Title:  "Association Study Between C282Y HFE Mutant, Iron, and Cholesterol for Neuroblastoma Treatment"
Funding Agency:  Children's Miracle Network
Period:  07/01/2014-06/30/2015
Amount:  $32,000

Title:  "Targeting Sphingosine Kinase 1 for Brain Tumors"
Funding Agency:  Jake Gittlen Foundation Cancer Research Award
Period:  10/01/2014-09/30/2015
Amount:  $50,000


James McInerney, M.D.
Principal Investigator:  Philip A. Villanueava, M.D.
Title:  "Surgical Trial in Traumatic Intracerebral Haemorrhage"
Funding Agency:  Newcastle General Hospital (National Institutes of Health)
Period:  02/14/2011-02/29/2016
Amount:  $58,661


Mark D. Meadowcroft, Ph.D.
Title:  "Micro-histological MRI of White Matter Cytoarchitecture in Alzheimers Disease"
Funding Agency:  National Institute on Aging (1 R03 AG0474361-01)
Period:  09/30/2014-04/30/2015
Amount:  $80,150


Elias Rizk, M.D.
Principal Investigator:  Joan T. Richtsmeier, Ph.D., Department of Anthropology, Pennsylvania State University
Role:  Consultant
Title:  "Midface and Upper Airway in Craniosynostosis"
Funding Agency:  National Institute of Dental and Craniofacial Research (1 RO1 DE022988-01)
Period:  08/10/2012-05/31/2017
Amount:  $621,667


Steven J. Schiff, M.D., Ph.D.
Title:  "Room Temperature Sensors for Sustainable Magnetic Imaging of the Brain"
Funding Agency:  Gustavus and Louise Pfeiffer Research Foundation
Period:  07/01/2014-06/30/2015
Amount:  $75,000

Title:  "CRCNS: Model Based Data Assimilation and Control of Sleep-Wake Regulation in Epilepsy"
Funding Agency:  National Institute of Biomedical Imaging and Bioengineering (1 R01 EB019804-01)
Period:  09/17/2014-05/31/2015
Amount:  $295,550

Co-Investigators:  Andrew Read, Ph.D., Department of Biology; Bruce J. Gluckman, Ph.D., Department of Engineering, Science and Mechanics/Department of Neurosurgery; Patrick Drew, Ph.D., Department of Engineering, Science and Mechanics/Department of Neurosurgery; Jose Antonio Stoute, M.D., Department of Infectious Disease
 Title:  "CRCNS:  Collaborative Research:  Model-Based Control of Spreading Depression"
Funding Agency:  National Institute of Biomedical Imaging and Bioengineering (5 R01 EB014641-03)
Period:  08/01/2012-07/31/2015
Amount:  $180,233

Title:  "A Murine Model for Preventing Postmalarial Epilepsy"
Funding Agency:  The Brighter Future Award, Citizens United for Research in Epilepsy (CURE)
Period:  09/01/2012-08/31/2015
Amount:  $350,000


J. Christopher Zacko, M.D.
Principal Investigator:  Adnan I. Qureshi, M.D., Department of Neurology
Primary Site:  University of Minnesota
Role:  Site Principal Investigator
Co-Investigators:  Raymond K. Reichwein, M.D., Department of Neurology, Robert E. Harbaugh, M.D., Kevin M. Cockroft, M.D., Jonas M. Sheehan, M.D., James McInerney, M.D., G. Timothy Reiter, M.D., Kimberly S. Harbaugh, M.D.
Title:  "A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction for Hypertension in Acute Intracerebral Hemorrhage – ATACH-II"
Funding Agency:  National Institutes of Neurological Disorders and Stroke
Period:  Extension pending
Amount:  $4,674  (06/22/2011-07/31/2013)
Supplemental Funds:  $39,590  (06/22/2011-07/31/2013)
Supplemental Funds:  $4,674