Pediatric Hematology/Oncology Overview

The Division of Pediatric Hematology/Oncology faculty are conducting cutting-edge basic, translational, and clinical cancer and hematology research aimed at understanding the fundamental mechanisms that lead to malignancy, as well as developing novel treatment strategies for childhood malignancy. Research areas include: the regulation of cell proliferation by intracellular signaling; tumor suppression in acute leukemia; the regulation of cellular senescence; accelerated drug discovery; immunotherapy for malignant diseases, and Phase I and II trials for malignant diseases.

The Division of Pediatric Hematology/Oncology participates in clinical trials through the Children's Oncology Group (COG) and the Pediatric Oncology Experimental Therapeutics Investigators' Consortium (POETIC).

Research faculty are internationally renowned physician-scientists. Research is supported by the National Institutes of Health, Four Diamonds, and other philanthropic organizations.

The Four Diamonds Pediatric Cancer Research Center was established in 1999 and is now supported by greater than thirty million dollars in endowments including the Penn State IFC/Panhellenic Dance Marathon Chair, the Christopher Millard Endowed Chair in Pediatric Oncology, the Experimental Therapeutics Program, and the Molecular Oncology Program.